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Epigenetic therapy in MDS and AML: focus on decitabine

✍ Scribed by M. Lübbert; P. W. Wijermans


Book ID
105988752
Publisher
Springer
Year
2006
Tongue
English
Weight
45 KB
Volume
85
Category
Article
ISSN
0939-5555

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## Abstract AML1/RUNX1 point mutations have been identified in myelodysplastic syndrome (MDS) and MDS‐related acute myeloid leukemia (AML), or MDS/AML, and are distributed throughout the full length of __AML1/RUNX1__. Gene mutation is proposed to be one of the disease‐defining genetic abnormalities