Epigenetic combination therapy as a tumo
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Sascha Venturelli; Sorin Armeanu; Anita Pathil; Chih-Jen Hsieh; Thomas S. Weiss;
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Article
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2007
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John Wiley and Sons
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English
β 259 KB
## Abstract ## BACKGROUND. Innovative epigenetic therapeutics comprise histone deacetylase inhibitors (HDACβI) and demethylating agents (DA). It was recently found that HDACβI compounds exhibit profound therapeutic activities against hepatocellular carcinoma (HCC). A comprehensive preclinical inve