Molecular targeted therapies in hepatoce
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Josep M. Llovet; Jordi Bruix
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Article
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2008
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John Wiley and Sons
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English
β 647 KB
Hepatocellular carcinoma (HCC) is a complex and heterogeneous tumor with several genomic alterations. There is evidence of aberrant activation of several signaling cascades such as epidermal growth factor receptor (EGFR), Ras/extracellular signal-regulated kinase, phosphoinositol 3-kinase/mammalian