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Epigenetic regulation of the X-linked tumour suppressors BEX1 and LDOC1 in oral squamous cell carcinoma

✍ Scribed by Lee, Chia-Huei; Wong, Thian-Sze; Chan, Jimmy Yu-Wai; Lu, Shao-Chun; Lin, Pinpin; Cheng, Ann-Joy; Chen, Yin-Ju; Chang, Jeffrey Shu-Ming; Hsiao, Shu-Huei; Leu, Yu-Wei; Li, Chuan-i; Hsiao, Jenn-Ren; Chang, Jang-Yang

Book ID
120388543
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
812 KB
Volume
230
Category
Article
ISSN
0022-3417

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## Abstract A high level of plasminogen activator inhibitor‐1 (PAI‐1 or __SERPINE1__) in tumor extracts is a marker of a poor prognosis in human cancers, including oral carcinomas. However, the mechanisms responsible for the upregulation of PAI‐1 in cancers remain unclear. Investigating specific PA