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Epigenetic regulation of bone morphogenetic protein-6 gene expression in breast cancer cells

✍ Scribed by Ming Zhang; Qing Wang; Wei Yuan; Shuang Yang; Xu Wang; Ji-Dong Yan; Jun Du; Jian Yin; Song-Yuan Gao; Bao-Cun Sun; Tian-Hui Zhu

Book ID
116698005
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
506 KB
Volume
105
Category
Article
ISSN
0960-0760

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Expression of bone morphogenetic protein
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Bone morphogenetic proteins (BMPs) are multifunctional regulators of proliferation, differentiation and apoptosis. BMP-6 is involved in numerous developmental processes. We have demonstrated expression of BMP-6 in breast cancer cell lines by RT-PCR and immuno-histochemistry. The level of BMP-6 mRNA