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Epigenetic Inactivation of Tumor Suppressor Genes in Serum of Patients with Cutaneous Melanoma

โœ Scribed by Marini, Alessandra; Mirmohammadsadegh, Alireza; Nambiar, Sandeep; Gustrau, Annett; Ruzicka, Thomas; Hengge, Ulrich R


Book ID
110049154
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
172 KB
Volume
126
Category
Article
ISSN
0022-202X

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## Abstract Tumor suppressor genes (TSGs) are sometimes inactivated by transcriptional silencing through promoter hypermethylation. To identify novel methylated TSGs in melanoma, we carried out global mRNA expression profiling on a panel of 12 melanoma cell lines treated with a combination of 5โ€Aza