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Epigenetic inactivation of the E-cadherin gene in eyelid sebaceous gland carcinoma

โœ Scribed by P. Jayaraj; S. Sen; A. Sharma; K. Chosdol; S. Kashyap; A. Rai; N. Pushker; M.S. Bajaj; S. Ghose


Book ID
114707345
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
380 KB
Volume
167
Category
Article
ISSN
0007-0963

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CpG methylation of promoter region inact
โœ Dana Nojima; Koichi Nakajima; Long-Cheng Li; Joseph Franks; Leopoldo Ribeiro-Fil ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 638 KB

CpG methylation in the promoter region has been shown to be important in the regulation of genes implicated in malignant transformation. The present study was designed to test the hypothesis that CpG methylation of the promoter region of the E-cadherin gene may inactivate its expression in renal cel