Epigenetic gene silencing in cancer initiation and progression
โ Scribed by Kenneth P. Nephew; Tim Hui-Ming Huang
- Book ID
- 117467558
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 252 KB
- Volume
- 190
- Category
- Article
- ISSN
- 0304-3835
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The human intestinal pathogen __Entamoeba histolytica__ has a number of virulence factors which can cause damage to the host. Transcriptional silencing of the gene coding for one of its major toxic molecules, the amoebapore (__Ehapโa__), occurred following the transfection of amoebic tr
Maspin is a tumor suppressor whose expression is lost in many advanced breast cancers. Maspin has been shown to inhibit cell motility, invasion and metastasis; however, its precise role in normal mammary epithelium remains to be elucidated. Although expression of maspin mRNA is low or absent in most