๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

โœ Scribed by WenYong Chen; Timothy K. Cooper; Cynthia A. Zahnow; Michael Overholtzer; Zhiquan Zhao; Marc Ladanyi; Judith E. Karp; Nalan Gokgoz; Jay S. Wunder; Irene L. Andrulis; Arnold J. Levine; Joseph L. Mankowski; Stephen B. Baylin

Book ID
113523469
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
775 KB
Volume
6
Category
Article
ISSN
1535-6108

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

What the papers say: p53 Loss of Functio
What the papers say: p53 Loss of Function: Implications for the Processes of Immortalization and Tumorigenesis
โœ Cathy A. Finlay ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 470 KB ๐Ÿ‘ 2 views

The complex process of cell immortalization and transformation is likely to involve the inactivation of growth regulatory genes. Mutations (deletions, missense mutations) in the p53 gene are the most frequently observed genetic alteration in human tumors, making p53 a candidate for a cellular protei