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Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines

✍ Scribed by Qiwei Yang; Yufeng Tian; Kelly R Ostler; Alexandre Chlenski; Lisa J Guerrero; Helen R Salwen; Lucy A Godley; Susan L Cohn


Book ID
115010069
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
830 KB
Volume
10
Category
Article
ISSN
1471-2407

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In order to clarify the relationship between invasiveness and loss of cellular differentiation in tumor cells, we studied the invasive properties on Matrigel of (a) a series of clones we isolated from human neuroblastoma LaN1 and Platt cell lines inducible to differentiation by adhesion on fibronect