## Abstract Plasminogen activator inhibitor typeβ1 (PAIβ1) is the major negative regulator of the plasminβdependent pericellular proteolytic cascade. PAIβ1 gene expression is normally growth state regulated but frequently elevated in chronic fibroproliferative and neoplastic diseases affecting both
Epidermal Morphogenesis: The Transcriptional Program of Human Keratinocytes during Stratification
β Scribed by Koria, Piyush; Andreadis, Stelios T
- Book ID
- 110049401
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 237 KB
- Volume
- 126
- Category
- Article
- ISSN
- 0022-202X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Nickel is a ubiquitous and virtually unavoidable environmental pollutant and occupational hazard, but its molecular and cellular effects are not well understood. Human epidermal keratinocytes are the sentinel and the primary target for nickel. We treated with nickel salts skin equivalen
Expression of the transglutaminase type1 gene (TGM1), which encodes an epithelial cell-specific protein cross-linking enzyme, is limited to particular stages of epidermal development and keratinocyte differentiation. As a result, transglutaminase type 1 (TGase1) enzyme activity in epidermal cells in
## Abstract The epidermal growth factor (EGF) receptor is highly expressed in HaCaT keratinocytes as shown by Western blotting. Stimulation of HaCaT cells with EGF, and also with the serine protease thrombin, induced DNA synthesis, measured by incorporation of 5βbromoβ2β²βdeoxyuridine into the DNA o