Growth and morphogenesis in the mammary gland depend on locally derived growth factors such as those in the epidermal growth factor (EGF) superfamily. Cripto-1 (CR-1, human; Cr-1, mouse)-also known as teratocarcinoma-derived growth factor-1-is a novel EGF-related protein that induces branching morph
Epidermal growth factor requirement for development of cultured mammary gland
โ Scribed by Tonelli, Quentin J.; Sorof, Sam
- Book ID
- 109718639
- Publisher
- Nature Publishing Group
- Year
- 1980
- Tongue
- English
- Weight
- 365 KB
- Volume
- 285
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/285250a0
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The purpose of the present studies was to investigate the role of epidermal growth factor (EGF) in the acquisition of estrogen (E) and progestin (P) responsiveness in the mouse mammary gland in vivo. Using the Elvax 40P implant technique to introduce bioactive molecules directly into the mammary gla