## Abstract A range of targetβbased agents for the treatment of solid tumors are in development. The epidermal growth factor receptor (EGFR) has been identified as a relevant target as it is involved in regulating several cellular functions important in the proliferation and survival of cancer cell
β¦ LIBER β¦
Epidermal growth factor receptor tyrosine kinase inhibitors
β Scribed by Ranson, M
- Book ID
- 109998092
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 98 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0007-0920
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## Abstract Small molecule epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have shown promising activity in patients with nonβsmall cell lung cancer (NSCLC). Gefitinib has been the first of these drugs to be licensed for thirdβline treatment of advanced NSCLC patients. Mor