Epidermal Growth Factor Receptor Inhibitors in the Treatment of Nonmelanoma Skin Cancers
β Scribed by MISBAH H. KHAN; MURAD ALAM; SIMON YOO
- Book ID
- 109078279
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 488 KB
- Volume
- 37
- Category
- Article
- ISSN
- 1076-0512
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Novel therapeutic agents that target the epidermal growth factor receptor (EGFR) constitute an important addition to the therapeutic armamentarium for the treatment of metastatic disease. EGFRβtargeted agents currently approved by the U.S. Food and Drug Administration include cetuximab,
Somatic mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR) gene in lung cancers have generated enormous interest, because they predict for sensitivity to TK inhibitors (TKIs). While mutational status is of great importance in determining response to TKIs, it