Epidermal growth factor receptor assay: Validation of a single point method and application to breast cancer
✍ Scribed by J. L. Formento; M. Francoual; P. Formento; M. C. Etienne; J. L. Fischel; M. Namer; M. Frenay; E. François; G. Milano
- Book ID
- 105315327
- Publisher
- Springer US
- Year
- 1991
- Tongue
- English
- Weight
- 622 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0167-6806
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Epidermal growth factor receptor (EGFr) assays were performed by 3 different methods on 246 human primary breast carcinomas. Scatchard analyses of multipoint binding data on 19 of the first 209 tumours, performed by a displacement method, demonstrated that the majority of tumours exhibited 2 classes
## Abstract Epidermal growth factor (EGF) receptor status is a useful prognostic indicator in women with breast cancer. Lack of standardization and correlation of methodology for the detection of EGF receptor has hampered its further evaluation. EGF receptor status was ascertained by immunohistoche