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Epidermal growth factor and platelet-derived growth factor induce expression of Egr-1, a zinc finger transcription factor, in human malignant glioma cells

✍ Scribed by Katrin Kaufmann; Gerald Thiel

Book ID
119465421
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
216 KB
Volume
189
Category
Article
ISSN
0022-510X

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## Abstract The epidermal growth factor (EGF) receptor is highly expressed in HaCaT keratinocytes as shown by Western blotting. Stimulation of HaCaT cells with EGF, and also with the serine protease thrombin, induced DNA synthesis, measured by incorporation of 5‐bromo‐2′‐deoxyuridine into the DNA o