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Epidemiology of hepatitis b e antigen and antibody in mentally retarded hbsag carriers

✍ Scribed by Ghanshyam Lohiya; Sunita Lohiya; Vinh Trong Ngo; Ramona Crinella

Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
264 KB
Volume
6
Category
Article
ISSN
0270-9139

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✦ Synopsis

Screening for HBeAg and anti-HBe WM performed on 133 carriers of HBsAg in an institution for the mentally retarded. By radioimmunoassay, the prevalences of HBeAg and anti-me were determined to be 16 and 78%, respectively. J3BeAg prevalence WM significantly different in the following pairs of carriers: 70% in blacks, 10% in whites, and 36% in carriers with Down's syndrome, 8% in carriers without Down's syndrome. Mean age of HBeAg-positive carriers (25.7 years) was lower than HBeAg-negative carriers (29.6 years, p < 0.05). SGPT levels were abnormal in 66% of HBeAg-positive and 26% of HBeAg-negative carriers (p < 0.01). This suggests an association between HBeAg positivity and functional liver impairment.

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