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Epidemiology of cardiac actin gene mutations in dilated cardiomyopathy

✍ Scribed by Ronald Zolty; Gary L. Brodsky; M. Benjamin Perryman; Michael R. Bristow; Luisa Mestroni


Book ID
119590074
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
130 KB
Volume
5
Category
Article
ISSN
1532-8414

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Mutational analysis of the cardiac actin
✍ Takai, Eiji; Akita, Hozuka; Shiga, Nobuyuki; Kanazawa, Kenji; Yamada, Shinichiro πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 14 KB πŸ‘ 2 views

Dilated cardiomyopathy (DCM) results in part from genetic disorders. Recently, missense mutations of the cardiac actin gene have been reported to cause DCM. We studied 136 Japanese DCM cases to elucidate how frequently the gene mutations are involved in its pathogenesis. Genomic DNA samples were obt