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Actin Mutations in Dilated Cardiomyopathy, a Heritable Form of Heart Failure

✍ Scribed by Olson, T. M.


Book ID
121159429
Publisher
American Association for the Advancement of Science
Year
1998
Tongue
English
Weight
359 KB
Volume
280
Category
Article
ISSN
0036-8075

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Mutational analysis of the cardiac actin
✍ Takai, Eiji; Akita, Hozuka; Shiga, Nobuyuki; Kanazawa, Kenji; Yamada, Shinichiro πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 14 KB πŸ‘ 2 views

Dilated cardiomyopathy (DCM) results in part from genetic disorders. Recently, missense mutations of the cardiac actin gene have been reported to cause DCM. We studied 136 Japanese DCM cases to elucidate how frequently the gene mutations are involved in its pathogenesis. Genomic DNA samples were obt