Eph Receptors and Ephrin Ligands: Essential Mediators of Vascular Development
✍ Scribed by Ralf H Adams; Rüdiger Klein
- Book ID
- 114341912
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 507 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1050-1738
No coin nor oath required. For personal study only.
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## Background The tissue distributions and functions of Eph receptors and their ephrin ligands have been well studied, however less is known about their evolutionary history. We have undertaken a phylogenetic analysis of Eph receptors and ephrins from a number of invertebrate and vertebrate species
## Abstract Eph receptors and their ephrin ligands constitute the largest subfamily of receptor tyrosine kinases and are components of the cell signaling pathways involved during development. Eph and ephrin overexpression have been documented in a variety of human cancers including gastrointestinal