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Epac and PKA cooperate in the control of endothelial barrier function and motility

✍ Scribed by Magdalena J. Lorenowicz; Mar Fernandez-Borja; Peter L. Hordijk


Book ID
113951745
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
62 KB
Volume
45
Category
Article
ISSN
1537-1891

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Epac/Rap and PKA are novel mechanisms of
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## Abstract Acute lung injury, sepsis, lung inflammation, and ventilator‐induced lung injury are life‐threatening conditions associated with lung vascular barrier dysfunction, which may lead to pulmonary edema. Increased levels of atrial natriuretic peptide (ANP) in lung circulation reported in the