Fifty percent of human colon carcinomas contain activating mutations in the K-ras gene. However, whether these alterations in K-ras affect the function of Ras proteins in growth factor (GF) signal transduction is not known. Here we have characterized a previously defined human colon carcinoma cell m
EP4upregulation of Ras signaling and feedback regulation of Ras in human colon tissues and cancer cells
β Scribed by Cheng-Hsun Wu; Yuan-Wei Shih; Chun-Hua Chang; Ting-Tsz Ou; Chi-Chou Huang; Jeng-Dong Hsu; Chau-Jong Wang
- Publisher
- Springer-Verlag
- Year
- 2010
- Tongue
- English
- Weight
- 644 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0340-5761
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