Autocrine transforming growth factor a (TGFa) activity and control mechanisms for its expression were examined in a representative clonal isolate (CBS4) of a well-differentiated human colon carcinoma cell line designated CBS. CBS4 cells expressed TGFa and its receptor, epidermal growth factor recept
โฆ LIBER โฆ
Activated K-ras is involved in regulation of integrin expression in human colon carcinoma cells
โ Scribed by Kira Schramm; Kerstin Krause; Alexandra Bittroff-Leben; Petra Goldin-Lang; Eckhard Thiel; Ernst-Dietrich Kreuser
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- French
- Weight
- 250 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0020-7136
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Down-regulation of the cell-surface adhesion molecule CD44 has been suggested to play an important role in tumor progression and metastasis of prostate cancer. CD44 is encoded by a gene that contains a CpG-rich region (CpG island) in its 5ะ regulatory sequence. We tried to assess whether hypermethyl