A synthetic route to stable-isotope-substituted L-phenyl-synthesized from both aromatic precursors by initial conversion into sodium phenylpyruvate and subsequent alanine is presented, which allows the introduction of 13 C, 15 N, and deuterium labels at any position or combination of transformation
Enzymic synthesis of isotopically labelled L-tyrosine
โ Scribed by J.E. Baldwin; S.C. Nga; A.J. Pratta; M.A. Russella; R.L. Dyerb
- Book ID
- 104227589
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- French
- Weight
- 113 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
L-Tyrosine specifically labelled with 13C and 15N has been enzymatically synthesised from achiral precursors in high yield and optical purity.
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