Enzymic conversion of thymidine 3′-monophosphate to thymidine 3′-diphosphate and 3′-triphosphate
✍ Scribed by C. Coutsogeorgopoulos; B. Hacker; R. Mantsavinos
- Book ID
- 115742329
- Publisher
- Elsevier Science
- Year
- 1966
- Weight
- 236 KB
- Volume
- 119
- Category
- Article
- ISSN
- 0005-2787
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📜 SIMILAR VOLUMES
## Abstract A suitably protected thymidine 3′,5′‐bis(4‐morpholinylphosphonate) derivative was converted into a derivative with two different 3′‐ and 5′‐phosphoryl functions.
## Abstract __Mycobacterium tuberculosis__ thymidine monophosphate kinase (TMPKmt) has recently been introduced as a potential target for the structure‐based design of anti‐tuberculosis drugs. Based on the TMPKmt X‐ray structure and previous S.A.R. studies, we synthesised the nucleoside analogues *
## Abstract Syntheses of N‐3(substituted) analogues of thymidine, N‐3([^18^F]fluorobutyl)thymidine ([^18^F]‐FBT) and N‐3([^18^F]fluoropentyl)thymidine ([^18^F]‐FPT) are reported. 1,4‐Butane diol and 1,5 pentane diol were converted to their tosyl derivatives **2** and **3** followed by conversion to