Desymmetrisation of 4-cyano-4-phenylcyclohexanone I has been achieved by enzyme-catalysed enantioselective alcoholysis with n-butanol of the derived rscemic enol acetate 2 in tetrahydrofuran. The absolute configuration of the enol acetate (-)-(S)-2 (100% e.e.) obtained was determined by X-my analysi
✦ LIBER ✦
Enzyme-Promoted Desymmetrisation of Prochiral Bis(cyanomethyl) Sulfoxide
✍ Scribed by Piotr Kiełbasiński; Michał Rachwalski; Marian Mikołajczyk; Małgorzata Szyrej; Michał W. Wieczorek; Roel Wijtmans; Floris P. J. T. Rutjes
- Book ID
- 101423593
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 88 KB
- Volume
- 349
- Category
- Article
- ISSN
- 1615-4150
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