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Enzyme immobilization on heparin

✍ Scribed by Torchilin, V. P. ;Il'Ina, E. V. ;Streltsova, Z. A. ;Smirnov, V. N. ;Chazov, E. I.

Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
271 KB
Volume
12
Category
Article
ISSN
0021-9304

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✦ Synopsis

Abstract

We describe the preparation and some of the properties of heparin‐bound α‐chymotrypsin that were obtained via activation of heparin with water‐soluble carbodiimide. Immobilized enzyme has unchanged kinetic characteristics toward low‐molecular‐weight and macromolecular substrates. The heparin‐bound enzymes could have a wide range of medical applications.

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