Electrode fouling and biocompatibility problems remain the greatest obstacles to developing a stable glucose sensor for continuous in aivo monitoring in whole blood. Nafion encapsulation successfully prevents electrode fouling, and substantially inproves the stability and performance of whole blood
Enzyme electrode for glucose determination in whole blood
β Scribed by T. Santoni; D. Santianni; A. Manzoni; S. Zanardi; M. Mascini
- Book ID
- 117224070
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 672 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0039-9140
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An amperometric enzyme electrode is described for the assay of urate in undiluted, unstirred whole blood. The electrode used Aspergillus flavus uricase (EC.1.7.3.3) cross-linked to bovine serum albumin by means of glutaraldehyde, sandwiched between a dimethyldichlorosilane-treated microporous polyca
We have prepared amperometric glucose sensitive electrodes with a composite active layer consisting of Nafion, glucose oxidase, and carbon-supported platinum particles. A particularly advantageous configuration results from the use of such a film on a gas diffusion electrode. We demonstrate that the