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Enzymatic synthesis of optically active δ-hydroxy-β-ketoalkanephosphonates

✍ Scribed by Yonghui Zhang; Chengfu Xu; Jinfeng Li; Chengye Yuan


Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
306 KB
Volume
14
Category
Article
ISSN
0957-4166

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Enzymatic synthesis of optically active
✍ Chengye Yuan; Chengfu Xu; Yonghui Zhang 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 193 KB

A number of 1-and 2-aminoalkanephosphonates were resolved with high enantioselectivity by Candida antarctica lipase B-catalyzed acetylation. By this method, optically pure aminoalkanephosphonates and amidoalkanephosphonates, the precursors of the corresponding aminoalkanephosphonic acids, were synth