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Enzymatic synthesis of isotopically labelled pyrimidine deoxyribonucleotides

✍ Scribed by Frank-Kamenetskaya; N. F. Myasoedov

Publisher
John Wiley and Sons
Year
1991
Tongue
French
Weight
396 KB
Volume
29
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

An enzymatic method is described which makes it possible to synthesize labelled pyrimidine deoxyribonucleotides from corresponding labelled ribonucleotides using the RDP‐reductase system of ether‐treated E. coli E125 cells. Ether‐treated cells have been used for the first time for preparative enzymatic synthesis of labelled biologically active compounds.

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