Synthesis and 11C-labelling of (E,E)-1-(
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Yanming Wang; Chester A. Mathis; Guo-feng Huang; Daniel P. Holt; Manik L. Debnat
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Article
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2002
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John Wiley and Sons
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French
⚖ 183 KB
## Abstract Carboxylic acid derivatives of the amyloid‐binding dye Congo red do not enter the brain well and are thus unable to serve as __in vivo__ amyloid‐imaging agents. A neutral amyloid probe, (__E__,__E__)‐1‐(3′,4′‐dihydroxystyryl)‐4‐(3′‐methoxy‐4′‐hydroxystyryl)benzene (**3**), devoid of any