Inostamycin, which was recently isolated from Streptomyces sp. MH816-AF15 as an inhibitor of cytidine 5'-diphosphate 1,2-diacyl-sn-glycerol (CDP-DG): inositol transferase, caused a G1-phase accumulation in the cell cycle of small cell lung carcinomas. To investigate whether the cytostatic effect of
Enzymatic Synthesis of [3H]Cytidine 5′-Diphospho-1,2-diacyl-sn-glycerol
✍ Scribed by Ming Zhao; Diego Rua; Amiya K. Hajra; Miriam L. Greenberg
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 98 KB
- Volume
- 258
- Category
- Article
- ISSN
- 0003-2697
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A synthetic approach comprising several studied modifications was applied to the preparation of snglycerol 1,2-di-g-linolenate 3-palmitate (4). Thereby, a convenient and mild synthetic method was elaborated, affording 4 from 1,2-O-isopropylidene-sn-glycerol (1) in an average yield of 65 ± 75% and an
## Abstract The acid catalyzed reaction of glycerol‐d~5~ with bromoacetaldehyde dimethyl acetal affords the corresponding 2‐bromomethyl‐4‐hydroxymethyl‐1,3‐dioxolane, which was treated with lithium iodide in 2‐butanone to afford the pentadeuterated domiodol 1 in high isotopic purity.