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Enzymatic separation of hardly separable mixtures of structural isomers

✍ Scribed by Shin Tanikawa; Keiko Suzuki; Machiko Ono; Hiroyuki Akita


Book ID
113803857
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
149 KB
Volume
31
Category
Article
ISSN
1381-1177

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Separation of cistrans-cyclohexanecarbox
✍ Kurt KΓΆnigsberger; Hector Luna; Kapa Prasad; Oljan Repic; Thomas J. Blacklock πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 French βš– 195 KB

4-Substituted cis/trans-cyclohexanecarboxylates have been separated into the isomers by enzymatic hydrolysis with lipase from Candida rugosa with very good selectivity. The enzyme preferentially recognizes diequatorial conformations.