𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Enzymatic Semisynthesis of Dicarba Analogs of Calcitonin

✍ Scribed by Václav čeřovský; Erich Wünsch; Johann Brass


Book ID
115132416
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
787 KB
Volume
247
Category
Article
ISSN
1432-1327

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Enzymatic semisynthesis of [Leu B30] ins
✍ SAKINA, KIYOSHI ;UENO, YOSHIHIKO ;OKA, TATSUSHI ;MORIHARA, KAZUYUKI 📂 Article 📅 2009 🏛 Wiley (Blackwell Publishing) 🌐 English ⚖ 476 KB
Semisynthesis and properties of some ins
✍ Ken Inouye; Kunio Watanabe; Yoshihiro Tochino; Masashi Kobayashi; Yukio Shigeta 📂 Article 📅 1981 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 723 KB

The trypsin-catalyzed coupling of bovine (Boc)z-desoctapeptide (B23-B30)-insulin with synthetic octapeptides, H-Gly-Xz-X3-X4-Thr-Pro-Lys(Boc)-Thr-OH (Xz = Phe or Ala, X3 = Phe or Ala, X4 = Tyr or Ala), followed by deprotection and purification produced the [AlaBZ4, ThrB30]-, [AlaBZ5, ThrBN] -, and [

Enzymatic semisynthesis of human insulin
✍ Kazuyuki Morihara 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 482 KB 👁 1 views

## Abstract Peptide bond formation can be enzymatically catalysed by the reverse reaction of proteases. Application is seen in the industrial production of human insulin. Human insulin derivative can be enzymatically prepared using either porcine insulin or the single chain B(1–29)‐A(1–21) insulin