Enzymatic resolution of naproxen
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Surrinder Koul; Rajinder Parshad; Subhash C. Taneja; Ghulam N. Qazi
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Article
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2003
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Elsevier Science
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English
⚖ 174 KB
Trichosporon sp. (TSL), a newly found strain isolated from a locally fermented cottage cheese has been found to be highly stereoselective in the resolution of (S)-(+)-naproxen (ee >99%, E 500) from the corresponding racemic methyl ester. The process of resolution using whole cells has been scaled up