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Enzymatic resolution of racemic lactones

✍ Scribed by L. Blanco; E. Guibé-Jampel; G. Rousseau


Book ID
104217520
Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
231 KB
Volume
29
Category
Article
ISSN
0040-4039

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## Abstract Preparation of chiral γ‐substituted‐γ‐lactones (**1**) through kinetic resolution is described. (__S__)‐(–)‐1‐Phenylethylamine (**2**) in the presence of anhydrous AlCl~3~ shows satisfactory levels of enantioselection in reaction with racemic γ‐substituted‐γ‐lactones **1,** where (__R__