✦ LIBER ✦

Enzymatic resolution of racemic bicyclic lactones by horse liver esterase

✍ Scribed by E Guibé-Jampel; G Rousseau; L Blanco

Book ID: 104232768
Publisher: Elsevier Science
Year: 1989
Tongue: French
Weight: 154 KB
Volume: 30
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)80324-5

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✦ Synopsis

Optically active lactones were prepared by Horse Liver esterase catalyzed hydrolysis of bicyclic 'y-butyrolactones. Horse Liver esterase (HLE) IS less employed in organic synthesis than Porcine Liver esterase

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Resolution of racemic 1-azaadamantane de

Resolution of racemic 1-azaadamantane derivatives by pig liver esterase catalysis

✍ Mölm, Detlef ;Risch, Nikolaus 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 205 KB

## Abstract The first kinetic resolution of racemic 1‐azaadamantane derivatives with PLE led to the enantiomers (−)‐1 and (−)‐2. An unexpected formation of 3 from 1 in aqueous solution was observed.