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Enzymatic resolution of (S)-(+)-naproxen in a continuous reactor

✍ Scribed by Ezio Battistel; Daniele Bianchi; Pietro Cesti; Carlo Pina

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
607 KB
Volume
38
Category
Article
ISSN
0006-3592

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## Abstract A lipase‐catalyzed enantioselective continuous hydrolysis process under __in situ__ racemization of substrate using sodium hydroxide as catalyst was developed for the production of __(S)__‐Naproxen from racemic Naproxen methyl ester in an aqueous–organic biphase system. Use of a tubular