Enzymatic and chemical labelling of pros
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Dimitrios Tsikas; Stefan Bracht; Dirk Stichtenoth; JΓΌrgen C. FrΓΆlich
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Article
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1993
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John Wiley and Sons
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French
β 447 KB
## Abstract Chemical and enzymatic tools were employed to synthesize [1,1β^18^O~2~]βprostaglandin (PG) E1, [1,1β^18^O~2~]β13,14βdihydroβ15βketoβPGE~1~ and [5,6β^3^H~2~]β13,14βdihydroβ15βketoβPGE~1~ starting from the corresponding unlabelled compounds adn [5,6β^3^H~2~]βPGE~1~, respectively. Reaction