Enzymatic hydrolysis byHumicola lanuginosalipase of poly(lactic acid)–poly(glycolic acid) monolayers
✍ Scribed by Tz. Ivanova; A. Svendsen; R. Verger; I. Panaiotov
- Book ID
- 106069626
- Publisher
- Springer
- Year
- 2000
- Weight
- 224 KB
- Volume
- 278
- Category
- Article
- ISSN
- 0340-255X
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## Abstract A novel PLA‐based polymer containing reactive pendent ketone or hydroxyl groups was synthesized by the copolymerization of L‐lactide with __ε__‐caprolactone‐based monomers. The polymer was activated with NPC, resulting in an amine‐reactive polymer which was then cast into thin polymeric
Poly(lactic acid) (PLA) and poly(lactic/glycolic acid) copolymers (PLGA) are biodegradable drug carriers of great importance, although successful pharmaceutical application requires adjustment of the surface properties of the polymeric drug delivery system to be compatible with the biological enviro