✦ LIBER ✦

Enzymatic formation of lactams in organic solvents

✍ Scribed by Arie L. Gutman; Elazar Meyer; Xu Yue; Chris Abell

Publisher: Elsevier Science
Year: 1992
Tongue: French
Weight: 238 KB
Volume: 33
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)74825-8

No coin nor oath required. For personal study only.

✦ Synopsis

Porcine pancreatic lipase in organic solvents catalyses the intramolecular cyclisation of aminoesters and the formation of macrczyctic bislactams from diesters and diamines.

In this Paper we report the enzyme-catalysed formation of lactams in organic solvents. In particular we have looked at (a) the formation of small ring lactams by intramolecular aminolysis of the corresponding aminoesters; and (b) the formation of macrocyclic bislactams via a bimolecular condensation of a diamine and a

📜 SIMILAR VOLUMES

Enzymatic analyses in organic solvents

✍ Rafi Z. Kazandjian; Jonathan S. Dordick; Alexander M. Klibanov 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 469 KB

Enzymatic catalysis in organic solvents

✍ Paul A. Burke; Alexander M. Klibanov 📂 Article 📅 1991 🏛 Elsevier Science ⚖ 75 KB

Asymmetric enzymatic oxidoreductions in

Asymmetric enzymatic oxidoreductions in organic solvents

✍ Alexander M Klibanov 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 106 KB

It is now beyond doubt that enzymes can vigorously work even in neat organic solvents containing little or no water. Switching the enzymatic reaction medium from aqueous to nonaqueous can make previously problematic processes feasible through, for example, increased substrate solubility or diminishe

Enzymatic transesterification of steroid

Enzymatic transesterification of steroid esters in organic solvents

✍ Vincent C.O. Njar; Eliahu Caspi 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 207 KB

Enzymatic polytransesterification of aro

Enzymatic polytransesterification of aromatic diols in organic solvents

✍ Hyun Gyu Park; Ho Nam Chang; Jonathan S. Dordick 📂 Article 📅 1995 🏛 Springer Netherlands 🌐 English ⚖ 300 KB

Enzymatic catalysis in cosolvent modifie

Enzymatic catalysis in cosolvent modified pressurized organic solvents

✍ Marazban Sarkari; Barbara L. Knutson; Ching-Shih Chen 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 154 KB

An important advantage of carrying out enzymatic catalysis in organic media is the increased solubility of hydrophobic substrates. This study compares a model lipase catalyzed esterification of cholesterol using vinyl acetate (VA) in two such nontraditional media: high-pressure hexane and supercriti