Naturally occurring enzymes may be modified by covalently attaching hydrophobic groups that render the enzyme soluble and active in organic solvents, and have the potential to greatly expand applications of enzymatic catalysis. The reduction of elemental sulfur to hydrogen sulfide by a hydrogenase i
Enzymatic catalysis in organic solvents
โ Scribed by Paul A. Burke; Alexander M. Klibanov
- Publisher
- Elsevier Science
- Year
- 1991
- Weight
- 75 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0923-1137
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
An important advantage of carrying out enzymatic catalysis in organic media is the increased solubility of hydrophobic substrates. This study compares a model lipase catalyzed esterification of cholesterol using vinyl acetate (VA) in two such nontraditional media: high-pressure hexane and supercriti
It is now beyond doubt that enzymes can vigorously work even in neat organic solvents containing little or no water. Switching the enzymatic reaction medium from aqueous to nonaqueous can make previously problematic processes feasible through, for example, increased substrate solubility or diminishe
Porcine pancreatic lipase in organic solvents catalyses the intramolecular cyclisation of aminoesters and the formation of macrczyctic bislactams from diesters and diamines. In this Paper we report the enzyme-catalysed formation of lactams in organic solvents. In particular we have looked at (a) th