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Enzymatic denitrification of 2-nitropropane in uninduced mouse liver microsomes

✍ Scribed by Marker, Elizabeth K.; Kulkarni, Arun P.

Book ID
122087063
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
396 KB
Volume
26
Category
Article
ISSN
0378-4274

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Cytochrome P-450β€”Mediated denitrificatio
Cytochrome P-450β€”Mediated denitrification of 2-nitropropane in mouse liver microsomes
✍ Marker, Elizabeth K. ;Kulkarni, Arun P. πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 802 KB

Enzymatic denitrification of 2-nitropropane (2NP) was investigated in an NADPH-dependent hepatic microsomal system from male CD1 mice. The involvement of cytochrome P-450 (P-450) as the catalyst in 2NP denitrification was revealed by the induction of nitrite-releasing activity following phenobarbita