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Cumene hydroperoxide-supported denitrification of 2-nitropropane in uninduced mouse liver microsomes

✍ Scribed by Elizabeth K. Marker; Arun P. Kulkarni


Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
707 KB
Volume
18
Category
Article
ISSN
0020-711X

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Cytochrome P-450—Mediated denitrificatio
✍ Marker, Elizabeth K. ;Kulkarni, Arun P. 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 802 KB

Enzymatic denitrification of 2-nitropropane (2NP) was investigated in an NADPH-dependent hepatic microsomal system from male CD1 mice. The involvement of cytochrome P-450 (P-450) as the catalyst in 2NP denitrification was revealed by the induction of nitrite-releasing activity following phenobarbita