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Enzymatic conversion of 5-tritiotryptophan to 4-tritio-5-hydroxytryptophan

โœ Scribed by Jean Renson; John Daly; Herbert Weissbach; Bernhard Witkop; Sidney Udenfriend

Book ID
118849846
Publisher
Elsevier Science
Year
1966
Tongue
English
Weight
489 KB
Volume
25
Category
Article
ISSN
0006-291X

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Enzymatic conversion of deoxycytidine 5โ€ฒ
Enzymatic conversion of deoxycytidine 5โ€ฒ-monophosphate to 5-methyldeoxycytidine 5โ€ฒ-triphosphate
โœ Richard Y.-H. Wang; Lan-Hsiang Huang; Melanie Ehrlich ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 465 KB

An enzymatic method has been developed to synthesize S-methyldeoxycytidine triphosphate (m'dCTP) starting with dCMP and formaldehyde as substrates. Methylation is catalyzed by a dCMP methyltransferase in the presence of tetrahydrofolic acid. The resulting m'dCMP is converted to m'dCTP by a kinase pr