ChemInform Abstract: Enzymatic Asymmetri
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A. FADEL; P. ARZEL
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Article
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2010
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John Wiley and Sons
⚖ 35 KB
Enzymatic Asymmetrization of Prochiral α,α-Disubstituted-malonates and -1,3-propanediols: Formal Asymmetric Syntheses of (-)-Aphanorphine and (+)-Eptazocine. -A method for the synthesis of the title compounds (X) and (XIII) is presented with a view to their analgesic activity. Two key intermediates