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Enzymatic alkylation of α-cyanoketones by bakers yeast

✍ Scribed by Andrew J. Smallridge; Abilio Ten; Maurie A. Trewhella

Book ID
104259458
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
204 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis

In an organic solvent system, 3-oxo-3-arylpropanenitriles are C-alkylated by bakers yeast. The reported mechanism for bakers yeast alkylation of ethyl cyanoacetate (13), in an

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Bakers′ Yeast Reduction of α-Diketones:
Bakers′ Yeast Reduction of α-Diketones: Investigation and Control of the Enzymatic Pathway
✍ P. Besse; J. Bolte; A. Fauve; H. Veschambre 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 537 KB

Optically pure \(\alpha\)-hydroxyketones and \(\alpha\)-diols are obtained through a regio- and stereocontrol of the reduction of acyclic \(\alpha\)-diketones by bakers' yeast. An investigation of the enzymatic system clearly demonstrates the role of two enzymes operating in sequence. An alcohol deh