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Environmental enrichment mitigates cognitive deficits in APP/PS1 transgenic mice

✍ Scribed by Joanna L. Jankowsky; Tatiana Melnikova; Daniel J. Fadale; Guilian M. Xu; Hilda H. Slunt; Victoria Gonzales; Linda H. Younkin; Steven G. Younkin; David R. Borchelt; Alena V. Savonenko

Book ID: 118461971
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 47 KB
Volume: 1
Category: Article
ISSN: 1552-5260
DOI: 10.1016/j.jalz.2005.06.342

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## Abstract Amyloid deposits are one of the hallmarks of Alzheimer's disease (AD), one of the most devastating neurodegenerative disorders. In transgenic mice modeling Alzheimer's pathology, the MR transverse relaxation time (__T__~2~) has been described to be modulated by amyloidosis. This modific