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Age-related changes in brain metabolites and cognitive function in APP/PS1 transgenic mice

โœ Scribed by Chen, Shuang-qing; Cai, Qing; Shen, Yu-ying; Wang, Pei-jun; Teng, Gao-jun; Zhang, Wei; Zang, Feng-chao

Book ID
119194301
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
548 KB
Volume
235
Category
Article
ISSN
0166-4328

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## Abstract Amyloid deposits are one of the hallmarks of Alzheimer's disease (AD), one of the most devastating neurodegenerative disorders. In transgenic mice modeling Alzheimer's pathology, the MR transverse relaxation time (__T__~2~) has been described to be modulated by amyloidosis. This modific