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Environmental and Gene-Environment Interactions and Risk of Rheumatoid Arthritis

✍ Scribed by Karlson, Elizabeth W.; Deane, Kevin


Book ID
122835873
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
377 KB
Volume
38
Category
Article
ISSN
0889-857X

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## Abstract ## Objective The main genetic risk factor for rheumatoid arthritis (RA) is the shared epitope (SE) of HLA–DR, while smoking is an important environmental risk factor. We studied a potential gene–environment interaction between SE genes and smoking in the etiology of the 2 major subgrou